biomarkerexpress™ is a suite of biomarker services that utilizes proprietary methods to significantly decrease timelines and increase the success rates traditionally associated with the various stages of biomarker development.

• Rapidly move from biomarker discovery through assay development to monitoring
• High specificity for targeted protein(s) including post-translational modifications and isoforms
• Multiplexing capabilities of greater than 20 proteins in a single assay
• Absolute or relative quantification based on mass spectrometry
• Not dependent on affinity reagents (no antibodies required)
• Small amount of sample required
• Applicable to biofluids, tissues, cells, formalin-fixed paraffin-embedded tissue, plants, etc.

Three components of biomarkerexpress™

discoveryexpress™

Biomarker discovery services:

• Differential and quantitative protein profiling
• High proteome and protein coverage
• Easy transition to biomarker assays

assayexpress™

Protein assay development services:

• Assay development time is weeks to months
• Optimized for multiplexing, short run times and lowest sample requirements
• High specificity for targeted protein(s) without affinity reagents

testingexpress™

Protein biomarker testing services:

• Monitoring of biomarkers in pre-clinical and clinical samples
• Verification and validation of putative biomarkers
• Quantification is not dependent on affinity reagents

The following PDF documents detail example project workflows:

• Biomarker workflow for biofluids biomarkers
• Biomarker workflow for cell and/or tissue biomarkers

Skip biomarker discovery and move right to assay development with your list(s) of biomarkers from:

• Proteomics experiments
• Transcriptomics experiments (genomics, genechips, microarrays)
• Pharmacogenomics experiments
• Literature and data mining

For more information, you can contact us here